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Last week's FDA advisory committee vote to add the peptide BPC-157 to the 503A compounding list based on a single, unpublished ulcerative colitis trial shocked fitness and wellness communities. Despite widespread off-label

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Our study indicates that inability of αSyn variants to refold into their native “inert” state likely causes chaperones to remain bound for extended periods beyond their biological timescale, thereby compromising normal chaperone activity