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Oral administration of PROTAC 52 in MV-4-11 xenograft models produced a good antitumor effect with tumor growth inhibition of around 77%, although lower than that obtained with the isolated use of the parent warhead gilterinib due to the poor pharmacokinetic characteristics of PROTAC (oral bioavailability of 5%)
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Si tras un estudio adecuado no encontramos ninguna causa que explique el problema le llamaremos infertilidad idiopática
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