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During persistent infections, however, chronic exposure to IL-10, TGF-β1, and TNFα could suppress ACTH-stimulated cortisol secretion in the adrenal gland and thus cause relative hypocortisolism (Fig
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The SemDΔAPH + SNX9-SH3 complex docking was done with CORAL 67 , based on the solved SemDΔAPH structure and an AlphaFold2 43,57 prediction of the interaction site from the SH3 domain with the flexible SemDΔAPH tail
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