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due to ageing or through acid-lowering medication), or bariatric surgery, lack of pancreatic enzymes, small intestinal bacterial overgrowth, certain intestinal parasites or dysfunction of the small intestine (e.g
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The folate-cobalamin interaction is pivotal for normal synthesis of purines and pyrimidines and the transfer of the methyl group to cobalamin is essential for the adequate supply of tetrahydrofolate, the substrate for metabolic steps that require folate
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