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Frontiers | Chuan Huang Fang combining reduced glutathione in treating acute kidney injury (grades 1–2) on chronic kidney disease (stages 2–4): A multicenter randomized controlled clinical trial
High levels of Hcy can activate the expression and release of inflammatory factors, leading to vascular endothelial dysfunction ( in vitro studies have corroborated the ability of Hcy to induce the release of inflammatory cytokines from ECs, including interleukin-6, interleukin-8, and tumor necrosis factor-α (Zhao et al., 2017)
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Functional MRI studies have demonstrated increased connectivity and activity in several brain regions, such as the insular cortex [73], amygdala [74], and somatosensory cortex [75]
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