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Clinical Use of Retinoids in Cancer Clinically, ATRA is the prototypical success story of retinoid oncology: in acute promyelocytic leukemia (APL), ATRA-based differentiation therapy (often combined with arsenic trioxide or anthracycline-based regimens) induces high complete remission rates and forms a cornerstone of modern APL management [310,318,319]
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[DOI] [PubMed] [Google Scholar] 90.Bellón T, González-Valle O, Sendagorta E, Lerma V, Martínez Del Río J, Martínez C, et al
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