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O’Donovan MC, Craddock NJ, Owen MJ
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Hence, phenotypic alterations observed when the function of the GPx4 5′UTR is compromised either by siRNA targeted at these sequences (Borchert et al., 2006) or by manipulating the expression of RNA-binding proteins such as Grsf1(Ufer et al., 2008) that bind these sequences reflect the importance of this regulatory mechanism for GPx4 expression
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