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To view the other articles in this section visit Abbreviations CBS cystathionine β‐synthase cPTIO 2‐(4‐carboxyphenyl)‐4,4,5,5‐tetramethylimidazoline‐1‐oxyl‐3‐oxide Cygb cytoglobin eNOS endothelial NOS Hb haemoglobin HfPEF heart failure with preserved ejection fraction I/R ischaemia–reperfusion mARC‐1 and mARC‐2 mitochondrial amidoxime‐reducing component–1 and 2 Mb myoglobin N 2 O 3 dinitrogen trioxide Ngb neuroglobin NiR nitrite reductase RSNO S‐nitrosothiol RBCs red blood cells sGC soluble GC XO xanthine oxidase Introduction We are celebrating the 20 th anniversary of the Nobel Prize awarded for the discovery of NO as a physiological signalling molecule with roles in neurobiology, immune defence and the regulation of cardiovascular homeostasis

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doi: 10.1002/j.1460-2075.1992.tb05055.x