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Although the clinical significance of vitamin B 12 deficiency remains unclear, our data suggest the need for routine vitamin B 12 monitoring in patients with type 2 diabetes, especially in metformin users of more than four years with average dose of over 1,000 mg per day, even in the absence of hematological abnormalities
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The MOTS-c literature is genuinely interesting, with rodent models showing effects on glucose handling and exercise capacity
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