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In addition, berberine can induce activation of PI3K/AKT signaling pathway, which is related to Nrf2 expression and neuroprotection ( via the microRNA (miR)-188/nitric oxide synthase 1 (NOS1) pathway ( In vitro experiments (organotypic hippocampal culture exposed to oxygen and glucose deprivation), the culture treated with berberine has less cellular death
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Type:BPC+PEA 500 (30 Capsules)
This deficiency worsens oxidative stress and contributes to complications, including symptoms like fatigue
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