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doi: 10.1006/abbi.1998.0914

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Contenance:940 ml (31.8 oz)

Those symptoms include: Chronic, inflammatory back pain with: (1) Age of onset below 40 years old, (2) insidious onset, (3) improvement with exercise, (4) no improvement with rest, and (5) pain at night (better upon getting up) Past history of inflammation in the joints, heels, or tendon attachments Family history for axial spondyloarthritis or other autoimmune conditions Positive for the gene HLA-B27 Good response to treatment with medications Signs of elevated inflammation, like a high SED rate Inflammatory bowel disease or eye inflammation MRI shows inflammation of the sacroiliac joint Osteoporosis with compression fractures and a back hump The first known case of AS in the United States was described in a pamphlet by David Tucker in 1858