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*Correspondence: Zhenyu Shi, [email protected] Qian, [email protected] † These authors have contributed equally to this work and share first authorship This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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Similarly, upregulating IDH3β or downregulating PAX6 could prevent phosphorylated tau accumulation, restoring synaptic protein expression and ameliorating pathological symptoms in 5xFAD mice [65]
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