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According to the American Dental Association, chronic dry mouth is also associated with: Oral candidiasis (thrush), a fungal infection that develops in the moist tissues of the mouth Burning mouth syndrome, a painful condition affecting the tongue and surrounding tissues Altered sense of taste Difficulty speaking and swallowing Denture discomfort, since saliva helps keep dentures properly seated and reduces irritation Patients often don’t realize their new cavities or worsening gum problems are connected to dry mouth, because they don’t feel particularly thirsty

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Each STAT member can be activated by a JAK via phosphorylation of a conserved tyrosine