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Consistent with Kidney Disease: Improving Global Outcomes (KDIGO) 2017—and reaffirmed by the 2024 KDIGO Controversies Conference—care should prioritize personalized management along bone (osteoporosis/fracture) and cardiovascular (calcification/left ventricular hypertrophy, LVH) axes: replete deficiency with nutritional vitamin D (D3 preferred
collagen-supplement
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This NO modulation affects blood flow, inflammation, and cellular signaling throughout healing tissues
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