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The 100 microgram dose of its booster shot was "generally safe and well tolerated," Moderna said, though "there was a trend toward slightly more frequent adverse reactions following the 100 [microgram] booster dose relative to the authorized 50 [microgram] dose." Without a booster, the company's vaccine, called mRNA-1273, was been found to be far less effective against the fast-spreading omicron variant, generating low neutralizing antibodies
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