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used IL-1β to simulate inflammation and FAC to simulate the iron overload state in chondrocytes ( 3.3 Ferroptosis and AS AS is a chronic disease characterized by inflammation of spinal attachment and sacroiliac joint, leading to spinal rigidity and fibrosis and may involve the eyes, lungs, muscle, and bone
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Also, the expression of PARP (as a substrate of caspase-3) was increased, which led to biochemical and morphological changes in the cells
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