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These results led the authors to suggest that mitochondrial CYP2E1 was able to cause the oxidative stress and cytotoxicity resulting from APAP exposure.20 Immunoblotting of liver samples from 30 different human donors using a panel of form-specific anti-CYP antibodies revealed substantial inter-individual variability in the amounts of these CYPs expressed in liver.21 Hence, it would be predicted that humans would show considerable inter-individual variability in their susceptibility to the hepatotoxicity of the drug
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Choose Your Bundle:16oz | 5 Pack
Yoritaka A, Hattori N, Uchida K, Tanaka M, Stadtman ER, Mizuno Y
Ships within 48 hours · Estimated delivery Oct 21 - Oct 26
US$40
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