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In this context, researchers focused on the roles of polymorphisms in antioxidant enzymes GPx1 ( GPX1 rs1050450) and SOD2 ( SOD2 rs4880), as well as the regulatory antioxidant protein nuclear factor erythroid 2-related factor 2 ( Nrf2 rs6721961) in shaping prostate cancer prognosis and development [139]
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