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Thiol-based redox metabolism of protozoan parasites - ScienceDirect
To determine whether these effects require intact phosphoinositide (PIP) signalling, we examined fibroblasts carrying mutations in MTMR5/SBF1, a catalytically inactive member of the myotubularin family involved in regulating PIP metabolism
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Excessive activation could theoretically lower seizure thresholds, promote excitotoxicity, or disrupt the balance between excitatory and inhibitory neurotransmission
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