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Antonoff MB, Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, Hofstetter WL, Swisher SG, Rice DC , Vaporciyan AA, Mehran RJ
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Further study based on an artificial model of GPX4 deletion in the proximal tubules indicated that knockout of GPX4 caused cell death in a pathologically relevant form of ferroptosis and spontaneous tubular necrosis, and the inhibition of ferroptosis by liproxstatin-1 was able to mitigate ischemia/reperfusion-induced tissue damage [85]
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