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In LPS-induced inflammatory mice, L-theanine treatment reduced the acute liver injury by inhibition of the concentrations of ALT and AST, the level of hepatic total superoxide dismutase (T-SOD), and malondialdehyde (MDA) ( With regard to kidney protection, in the doxorubicin (DOX) induced acute nephrotoxicity rat models, it was found that the treatment with L-theanine could attenuate the decrease of creatinine clearance, inhibit the production of lipid peroxidation in the kidney, and inhibit the reduction of glutathione content and SOD activity after DOX administration (90)