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Currently, clinically relevant DDIs can be queried through online and offline interaction checkers, such as Drugs, Lexi-Interact, and ePocrates, but the available clinical dosage suggestions are limited ( To date, several studies have developed PBPK models to predict the PK profiles of busulfan, phenytoin, voriconazole, posaconazole, itraconazole, fluconazole, letermovir, omeprazole, cyclosporine, tacrolimus, and sirolimus (Supplementary Table S1)
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Carruthers BM, Sande MIvde, Meirleir KLDe, Klimas NG, Broderick G, Mitchell T, et al
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