glutathione scavenger in slovenian Frontiers Model:SD-GTB8

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1 Introduction Methanol (CH 3 OH) is a common industrial solvent widely used in industries such as chemistry, pharmaceuticals, and cosmetics ( Although standard treatments for methanol poisoning, including hemodialysis, correction of acidosis, and administration of ethanol, have significantly improved patient survival rates, methanol poisoning remains a major clinical challenge

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Model:SD-GTB8

Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation