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However, the elevation in transcript level was found to be higher in case of thermo-tolerant genotypes (Almeselmani et al., 2013)
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Bei Patienten mit terminaler Niereninsuffizienz sollte an Hämodialyse-Tagen eine Supplementärdosis von Topiramat, die ungefähr der Hälfte der Tagesdosis entspricht, verabreicht werden, da Topiramat durch Hämodialyse aus dem Plasma entfernt wird Die Supplementärdosis sollte in Teildosen zu Beginn und nach Beendigung der Hämodialyse verabreicht werden
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