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cysteine glutathione new genetic code degruyther synthesis from Size:UK4 / EU37 / US6 / AU6 - WIDE FIT
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Results Chronic iron accumulation and GSH depletion remodel labile iron pools and induce ferritin expression Our experimental design employed two complementary stress paradigms: (1) chronic iron accumulation to model age-related brain iron overload and (2) chronic GSH depletion using buthionine sulfoximine (BSO) to investigate the role of GSH loss independent of exogenous iron, since preliminary observations suggested a mechanistic link between iron and GSH dysregulation
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