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AX may influence Polyunsaturated fatty acid (PUFA) metabolism through the modulation of fatty acid composition and the prevention of oxidative degradation rather than by directly stimulating PUFA biosynthesis [81]
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Little is known about the role of the lumenal cysteines in PERK activation, though dimerization and reduction contribute to activation and inactivation, respectively (Eletto et al., 2014a
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