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5-Amino-1MQ works upstream of the scale. It inhibits NNMT, an enzyme highly active inside fat tissue that depletes NAD+ and drives adipocyte expansion. When NNMT runs high, the cellular environment favors storage
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J Pharmacol Exp Ther 333:161–173 [DOI] [PMC free article] [PubMed] [Google Scholar] Youles M, Holmes O, Petoukhov MV, Nessen MA, Stivala S, Svergun DI, Gherardi E
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