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Pretibial myxedema treated with intralesional tumescent drug delivery of hyaluronidase, triamcinolone, vitamin B12, and sodium bicarbonate dissolved in a tumescent epinephrine lidocaine solution - ScienceDirect
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Similarly, a recently performed randomized, double-blind, placebo-controlled trial concluded that the treatment of metformin-treated patients with diabetic neuropathy with 1 mg of oral methylcobalamin for twelve months improved plasma B12 levels and improved all neurophysiological symptoms[56]
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