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Research has shown associations with: Collagen and elastin synthesis — upregulation in fibroblast and skin cell models Glycosaminoglycan and proteoglycan expression — including decorin and versican, relevant to extracellular matrix remodelling Contraction and granulation tissue formation — accelerated wound closure in animal models Anti-inflammatory signalling — reduction in pro-inflammatory cytokine activity in wound environments One notable study examined how the GHK-Cu complex modulated glycosaminoglycan and small proteoglycan expression in wounds, finding significant changes in extracellular matrix composition compared to controls, consistent with a role in organised tissue repair rather than disorganised scar formation