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Vitamin D deficiency is one of the abnormalities evaluated because vitamin D signaling can influence: Serotonin-related pathways Gene transcription Immune regulation Inflammatory signaling Brain development and function Cellular energy and muscle function Vitamin D status is therefore particularly relevant in patients being evaluated for: Depression Seasonal mood symptoms Anxiety ADHD or behavioral concerns Autism-spectrum or developmental concerns Fatigue Sleep disturbance Inflammatory or immune symptoms Vitamin D and Undermethylation Vitamin D does not directly diagnose undermethylation, but it can be an important supporting factor in an undermethylated patient
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Transl Psychiatry 7 , e1126 (2017)
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