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In sufficiently acidic environments, both carboxyl groups are protonated and the molecule becomes a cation with a single positive charge, HOOC−CH(NH + 3 )−(CH 2 ) 2 −COOH
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Pulmonary fibrosis and pulmonary hypertension (PAH) are observed in most of these patients due to increased serum levels of TNF-α (92)
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