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Autism spectrum disorder: insights into convergent mechanisms from transcriptomics
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In short, after a stressor is perceived via sensory inputs to the central nervous system, corticotrophin-releasing hormone (CRH) is synthesized and secreted from neurons in the paraventricular nucleus of the hypothalamus (PVH) into the median eminence, reaching proopiomelanocortin (POMC)-containing cells in the anterior lobe of the pituitary via the hypophyseal portal system
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