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Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children - Shroads - 2015 - The Journal of Clinical Pharmacology - Wiley Online Library

The TRE is composed of repeated DNA sequences with different configurations

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In our study, we observed that four of the Trp derivatives (5-hydroxy-L-tryptophan, indole-3-acetate, tryptamine and indolepyruvate) and two of the Phe derivatives (salicylate and shikimate) could activate the AhR in a dose-dependent manner (Fig